Eur J Anat, 22 (3): 221-225 (2018)

Human sexual dimorphism of the relative cerebral area volumes in the data of the human connectome project

Balázs Szalkai¹, Vince Grolmusz^1,2

¹ PIT Bioinformatics Group, Eötvös University, H-1117 Budapest, Hungary,² Uratim Ltd., H-1118 Budapest, Hungary

ABSTRACT The average human brain volume of males is larger than that of females. Several MRI voxel-based morphometry studies show that the gray matter/white matter ratio is larger in females. Here we have analyzed the recent public release of the Human Connectome Project, and by using the data of 511 subjects (209 men and 302 women), we have found that the volumes of numerous subcortical areas and most cortical areas, normalized by the total brain mask volume, are significantly larger in women than in men. Additionally, we have discovered that, for multiple brain regions, the correlation of the size of the left and right part is different between the sexes.

Keywords: Morphometry â?? FreeSurfer â?? Human Connectome Project â?? Sexual dimorphism â?? Cerebral area volumes