European Journal of Anatomy

Official Journal of The Spanish Society of Anatomy
Cover Volume 8 - Number 1
Eur J Anat, 8 (1): 17-23 (2004)

Connection between the arcuate nucleus and the posterior lobe of the hypophysis. An angiotensin II immunohistochemical study in rats

Perez-Gonzalez H., Carmona-Calero E., Martinez-Pena Y Valenzuela I., Castaneyra-Martin M., Ormazabal-Ramos C., Gonzalez-Marrero I., Monge-Casafranca C.R., Castaneyra-Perdomo A., Ferres-Torres R.

Dpto. de Anatomía, Facultad de Medicina, Universidad de La Laguna, Tenerife, Spain; Dpto. de Biotecnología, Inst. de Investigacion y Ciencias, Puerto del Rosario, Fuerteventura, Spain; Dpto. de Pediatría, Facultad de Medicina, Universidad de La Laguna, Tenerife, Spain; Departamento de Anatomía, Facultad de Medicina, Universidad de La Laguna, 38320 Tenerife, Spain

ABSTRACT The aim of this study was to perform an immunohistochemical study of the, angiotensinergic pathway from the arcuate nucleus (AN) to the posterior lobe of the hypophysis (PLH) of 10-week-old matched normotensive Wistar Kyoto rats (WKY), using our own policlonal antibody raised in mice against Angiotensin II (mouseantiangiotensin II, MAAII). Cells and fibers in the rostroventral and dorsocaudal parts of the AN, the internal zone of the median eminence and PLH showed immunoreactive material for antiangiotensin II. Angiontensin II fibers originating in the anteroventral part of the AN, crossing median eminence (ME) and infundibular stem and arriving at the PLH were also observed.

Keywords: angiotensin, polyclonal antibody, animal experiment, animal tissue, arcuate nucleus, article, hypophysis cell, immunocompetent cell, immunohistochemistry, infundibulum, male, median eminence, microscopic anatomy, nerve fiber, neurohypophysis, nonhuman, rat, rat strain

European Journal of anatomy
ISSN 2340-311X (Online)